Publications supported by the Research Training Group 1459 grant 2009




Sequence requirements for the export of the Plasmodium falciparum Maurer’s clefts protein REX2
Silvia Haase, Susann Herrmann,Christof Grüring, Arlett Heiber, Pascal W. Jansen,Christine Langer, Moritz Treeck,Ana Cabrera,Caroline Bruns, Nicole S. Struck, Maya Kono,Klemens Engelberg, Ulrike Ruch, Hendrik G. Stunnenberg, Tim-Wolf Gilberger1** and Tobias Spielmann
Molecular Microbiology (2009) 71(4), 1003–1017...Abstract


Glycosylation- and phosphorylation-dependent intracellular transport of lysosomal hydrolases
Sandra Pohl, Katrin Marschner, Stephan Storch, and Thomas Braulke
Biol Chem. 2009 Jul;390(7):521-7. Review


Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function
Paul Saftig and Judit Klumperman
Nat Rev Mol Cell Biol. 2009 Sep;10(9):623-35. Review.


Disease-causing mutations within the lysosomal integral membrane protein type 2 (LIMP-2) reveal the nature of binding to its ligand {beta}-glucocerebrosidase.
Blanz J, Groth J, Zachos C, Wehling C, Saftig P, Schwake M.
Hum Mol Genet. 2010; 19:563-572...Abstract


Loss of N-acetylglucosamine-1-phosphotransferase gamma subunit due to intronic mutation in GNPTG causes mucolipidosis type III gamma: Implications for molecular and cellular diagnostics.
Pohl S, Encarnacão M, Castrichini M, Müller-Loennies S, Muschol N, Braulke T.
Am J Med Genet A. 2010 Jan;152A(1):124-32. ...Abstract


Mannose phosphorylation in health and disease.
Kollmann K, Pohl S, Marschner K, Encarnação M, Sakwa I, Tiede S, Poorthuis BJ, Lübke T, Müller-Loennies S, Storch S, Braulke T.
Eur J Cell Biol. 2010;89:117-123....Abstract


Lysosomal targeting of the CLN7 membrane glycoprotein and transport via the plasma membrane require a dileucine motif.
Steenhuis P, Herder S, Gelis S, Braulke T, Storch S.
Traffic 2010; 11:987-1000 ....Abstract


Proteolytic processing of the {γ}-subunit is associated with the failure to form GlcNAc-1-phosphotransferase complexes and mannose 6-phosphate residues on lysosomal enzymes in human macrophages.
Pohl S, Tiede S, Marschner K, Encarnacao M, Castrichini M, Kollmann K, Muschol N, Ullrich K, Mueller-Loennies S, Braulke T.
J Biol Chem 2010; 285:23936-23944....Abstract

News

Seminar
“The Secret Life of Lysosomes”
Norma Andrews
University of Maryland
10.09.2010
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